Nurofen Plus - Ibuprofen and Codeine - 32 Tablets

Nurofen Plus is a combination pain relief medication containing ibuprofen (200mg) and codeine phosphate (12.8mg) per tablet. It is designed for short-term relief of moderate pain that is not alleviated by standard painkillers such as paracetamol, ibuprofen, or aspirin alone.

What is Nurofen Plus Used For?

Nurofen Plus tablets provide effective relief from:

• Migraine and headaches
• Neuralgia
• Period pain
• Dental pain
• Back pain
• Rheumatic and muscular pain

Due to the presence of codeine, which belongs to the opioid class of medicines, Nurofen Plus 32 tablets should only be used when other pain relief options do not provide adequate relief.

How Does Nurofen Plus Work?

The ibuprofen in Nurofen Plus is a non-steroidal anti-inflammatory drug (NSAID) that works by reducing inflammation and pain. Codeine phosphate, an opioid analgesic, works by modifying the body's perception of pain, providing stronger relief.

How to Take Nurofen Plus

• Adults, the elderly, and children aged 12 years and older:
• Take 1 or 2 tablets with water up to three times a day as required.
• Leave at least 4 hours between doses.
• Do not take more than 6 tablets in 24 hours.
• Do not take for more than 3 consecutive days without medical advice.
• Children under 12 years: Do not use due to the risk of severe breathing problems.
• If symptoms persist or worsen after 3 days, consult a doctor.

Addiction and Dependence Warning

Nurofen Plus contains codeine, which can cause addiction if taken continuously for more than three days. Signs of dependence include:

• Taking more than the recommended dose.
• Using the medicine for non-medical reasons, such as to stay calm or help with sleep.
• Experiencing withdrawal symptoms when stopping the medication.

If you feel you may be dependent on Nurofen Plus tablets, speak to a doctor or pharmacist immediately.

Warnings and Precautions

Do Not Take Nurofen Plus If You:

• Are allergic to ibuprofen, codeine, or any other NSAID.
• Have breathing difficulties.
• Have or have had stomach ulcers, perforation, or bleeding.
• Have severe kidney, liver, or heart problems.
• Are taking other NSAIDs (e.g., high-dose aspirin).
• Are pregnant or breastfeeding.
• Are under 12 years old.

Speak to a Doctor Before Taking If You:

• Have asthma or a history of allergic reactions to painkillers.
• Have a history of gastrointestinal diseases (e.g., Crohn’s disease, ulcerative colitis).
• Have heart problems, high blood pressure, diabetes, or high cholesterol.
• Have low blood pressure, dehydration, or thyroid disorders.
• Have a history of mental health disorders or substance abuse.

Use in Pregnancy and Breastfeeding

• Do not take Nurofen Plus if you are in the last 3 months of pregnancy, as it may cause harm to your baby.
• Do not take Nurofen Plus while breastfeeding, as codeine passes into breast milk and can cause serious harm to the baby.
• If you are in the first 6 months of pregnancy, consult a doctor before use.

Effects on Driving and Machinery

• Nurofen Plus may cause drowsiness, dizziness, or sleepiness.
• Do not drive or operate machinery until you know how it affects you.
• In the UK, it may be an offence to drive under the influence of codeine if it impairs your ability to drive safely.

Interactions with Other Medicines

Avoid taking Nurofen Plus 32 tablets with:

• Other opioid painkillers (e.g., morphine, tramadol).
• Antidepressants, sedatives, or sleep medications.
• Blood-thinning medications (e.g., warfarin).
• High blood pressure medications (e.g., beta-blockers, ACE inhibitors).
• Diuretics (water tablets).

Always check with your doctor or pharmacist before combining Nurofen Plus with other medications.

Possible Side Effects

Stop Taking Nurofen Plus and Seek Immediate Medical Help If You Experience:

• Severe allergic reactions (swelling of the face, wheezing, breathing difficulties).
• Intestinal bleeding (vomiting blood, black stools).
• Serious skin reactions (rash, blisters, peeling skin).
• Liver problems (yellowing of the skin, dark urine).

Other Possible Side Effects Include:

• Nausea, vomiting, indigestion, or stomach pain.
• Headache, dizziness, or drowsiness.
• Skin rash or itching.
• Constipation (due to codeine).

Long-term use can lead to kidney problems, dependency, or increased sensitivity to pain. If you notice any unusual symptoms, consult your doctor or pharmacist.

How to Store Nurofen Plus

• Store below 25°C in the original packaging.
• Keep out of reach of children.
• Do not use after the expiry date printed on the packaging.

Additional Information

Each tablet contains:

• 200mg Ibuprofen
• 12.8mg Codeine Phosphate
• Other inactive ingredients including microcrystalline cellulose, pregelatinised starch, and talc.

Disclaimer: While we strive to provide accurate and up-to-date information, we are not responsible for any discrepancies or issues that may arise. The information provided should not be used as a substitute for professional medical advice. Always consult your physician or a qualified healthcare provider for any questions you may have regarding a medical condition or treatment.